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Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.
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Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency Askoy
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Cell Sci. The implications of these findings are unknown.
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A Nature Research Journal. These cells acquire growth properties, a gene expression profile and an Harstad slut list landscape closer to those described in mouse naive PSCs. Together, these results show that temporarily increasing STAT3 activity is sufficient to reprogramme human PSCs to naive-like pluripotent cells.
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