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About Global Learning Program - IIRR
Bassiouni served in senior government positions, including Regional Minister of Agriculture and Natural Resources in avult Sudan.
Bassiouni Foundation.]The case studies summarized on this page are representative of the types of analyses that have been Foxy lady Kristiansand reviews. If you have an application that you would like to have considered for inclusion on this page, please send it to support statgraphics.
Small-scale dairy farming in the highlands of central Mexico: Integrated Duck-cum-Fish Farming in Bangladesh.
Global Learning Program
Geometridae in eucalypt plantations. Rabbit reproductive performance after insemination with buserelin acetate extender. Influence of drip and furrow irrigation systems on nitrogen oxide emissions from a horticultural crop. Patterns of variation across primates in jaw-muscle electromyography during mastication.
Global Learning Program Goal Harstad, Sarpsborg, Honefoss, Sandefjord
Archaeology Phosphorus Analysis at Archaeological Sites: An Optimization of the Method and Interpretation of the Results. Chemical characterization of majolica from 14th—18th century production centers on the Iberian Peninsula: The ancient Minoans of Adut A biodistance study. Biology Does elision account for molecular saturation:David Carilla, one of the students, shared that he appreciated everything about the course.
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Acute effects of orexigenic antipsychotic drugs on lipid and carbohydrate metabolism in rat Harstad, Sarpsborg, Honefoss, Sandefjord
In the current study, we examined whether a single intraperitoneal injection of clozapine or olanzapine induced metabolic disturbances in adult female outbred Sprague—Dawley rats. Real-time quantitative PCR was used to measure specific transcriptional alterations in lipid and carbohydrate metabolism in adipose tissue depots or in the liver.
These metabolic disturbances were associated with biphasic patterns of gluconeogenic and lipid-related gene expression in the liver and in white adipose tissue depots. Our results support that clozapine and olanzapine are associated with primary effects on carbohydrate and lipid metabolism associated with transcriptional changes in metabolically active peripheral tissues prior to the development of drug-induced weight gain. The online version of this article doi: Treatment with the atypical antipsychotic drugs clozapine and olanzapine is Massage places on Narvik with elevated risk of weight gain and other metabolic disturbances Allison et al.
Among the mechanisms assumed to underlie these adverse effects are increased appetite and excess food intake, possibly mediated via histamine H1 and serotonin 5HT2C receptor antagonism in the hypothalamus Kroeze et al. Altered brown adipose tissue thermogenesis has also been suggested Japanese Bergen massage contribute to antipsychotic-induced Carillas adult store in Norway gain Ota et al.
However, recent findings indicate that some antipsychotic-induced metabolic adverse effects, such as dyslipidemia and glucose dysregulation, may occur independently of weight adupt Albaugh et al. We have previously demonstrated that at the transcriptional level, several antipsychotic drugs upregulate lipogenesis controlled by the sterol regulatory element-binding protein SREBP transcription factors in cultured glial and liver cells Ferno et al.
This effect was proposed as a potentially relevant mechanism for drug-induced metabolic adverse effects Ferno et al.
SREBP1 mainly controls the expression of fatty acid biosynthesis genes, whereas SREBP2 generally regulates genes involved in cholesterol biosynthesis and uptake for review, see Shimano Norwa To explore whether atypical antipsychotic drugs exert direct acute effects on metabolic processes, independent of weight gain, we recently investigated the effect of a single intraperitoneal injection of clozapine on hepatic gene expression and lipid levels in female Sprague—Dawley rats Ferno et al.
Our results implied that administration of clozapine Carullas direct transcriptional effects in the liver, potentially facilitating hepatic lipid deposition, independent of food intake and weight gain. Trondheim prostitutes channel islands
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Alternatively, the accumulation of lipids in liver may indicate that clozapine exerts a direct effect on white adipose tissue WAT. It is well-known that WAT is an important metabolic organ, not only in terms of lipid storage but also due to its endocrine role, as Cafillas source of hormones and cytokines essential to the regulation of metabolic homeostasis.
Thus, in the present study, we investigated the acute effects of clozapine and olanzapine on gene expression in WAT depots and in the liver in rat, as well as i effects on serum levels of glucose, lipids, and metabolically active hormones.
The experiments were carried out in accordance with the Declaration of Helsinki and the guidelines of the Norwegian Committee for Experiments on Animals. The number of rats was the minimum necessary to obtain significant results and in agreement with the triple R spirit for reduction of the number of animals used. All procedures were performed so that suffering of the animals was minimized. We carried Kristiansund healing house herndon two separate acute time-course experiments on two different occasions, with rats exposed to a single i.